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As with other CNS acting drugs bupropion may affect ability to perform tasks that require judgement or motor and cognitive skillsZyban has also been reported to cause dizziness and lightheadednessPatients should therefore exercise caution before driving or use of machinery until they are reasonably certain Zyban does not adversely affect their performance.

Zyban may cause seizuresespecially if you have certain medical conditions or use certain drugsTell your doctor about all of your medical conditions and the drugs you use.

Studies suggest that exposure to bupropion may be increased when sustained release bupropion tablets are taken with a high fat mealsee section 5.2

Taking MAO inhibitors with this medication may cause a seriouspossibly fataldrug interactionAvoid taking MAO inhibitorsisocarboxazidlinezolidmethylene bluemoclobemidephenelzineprocarbazinerasagilinesafinamideselegilinetranylcypromineduring treatment with this medicationMost MAO inhibitors should also not be taken for two weeks before and after treatment with this medicationAsk your doctor when to start or stop taking this medication.

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